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Rheumatoid arthritis (RA) is a progressive inflammatory disorder characterized by proliferation of the synovial membrane and persistent uncontrolled inflammation resulting in a chronic destructive polyarthritis. Typically, RA manifests as a symmetric arthritis involving numerous small and large joints. Articular symptoms may be accompanied by systemic inflammatory symptoms such as fatigue, articular stiffness, anorexia, or fever.

Source: Healio

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